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Pilules Contraceptives Classification Essay

CLASSIFICATION

DES PILULES CONTRACEPTIVES

Par AMSTER

ATTENTION

Cet article a été reformuler

Voir notre mise à jour du 19 décembre 2017 sur

http://pharamster.over-blog.com/2017/12/classification-des-pilules-contraceptives.html

 

Article publié dans une revue marocaine en 2005

Mise à jour du 27/06/11

 

Ce tableau, non exhaustif,  prend en considération pour la classification des estroprogestatifs 4 paramètres :

1 - Les propriétés pharmacologiques du progestatif, en particulier son éventuel effet androgène. Les trois progestatifs n'ayant que peu ou pas de propriétés androgènes sont le désogestrel, le gestodène et le norgestimate.

2 - La quantité d'éthinylestradiol par comprimé: quand elle est inférieure à 40  microgrammes on parle de pilule minidosée, quand elle est égale à 50 microgrammes on parle de pilule normodosée.

3 - La combinaison monophasique, biphasique ou triphasique, cette dernière se rapprochant plus du cycle physiologique.

4 - Le prix, les pilules contraceptives n’étant pas remboursées le facteur prix joue un rôle important dans la poursuite de son utilisation   

- Pour affiner la pharmacodynamie des estrogènes et des progestatifs nous vous invitons à consulter notre page « La balance estroprogestative »

- PS du 18/12/12 : à lire aussi notre article POUR UNE DISPENSATION OFFICNALE RATIONNELLE ET SECURISEE DES CONTRACEPTIFS ORAUX  

Abréviations utilisées :

- EE : Ethinylestradiol

- IP  : Indice de Pearl : nombre de grossesses accidentelles x 100 x 12/nombre de cycles d’observations. Cela correspond au nombre de grossesses observées pour 100 femmes utilisant une contraception donnée durant un an.

 

Les pilules estroprogestatives

Progestatifs 1ère  Génération :

           Noréthistérone et ses pro-drogues : acétate de noréthistérone et lynestrénol

TRIELLA®  17.90 DH           

Minidosé Triphasique

IP :

Noréthistérone    0.50 mg     EE 0.035 mg   x 07  cp 

Noréthistérone    0.75 mg     EE 0.035 mg   x 07  cp 

Noréthistérone    1.00 mg     EE 0.035 mg   x 07  cp     

 

Progestatifs 2ème Génération :

           Norgestrel et Lévonorgestrel

STEDERIL® 11.65 DH      

Normodosé Monophasique

IP : 0.00

Norgestrel         0.50   mg      EE 0.05 mg  x  21 cp

ADEPAL®  

 13.90 DH

Minidosé

Biphasique

IP : 0.00

Lévonorgestrel  0.15   mg      EE 0.03 mg  x 07  cp Lévonorgestrel  0.20   mg      EE 0.04 mg  x 14  cp  

MINIDRIL®              

9.05DH                   

MICROGYNON®    

8.80DH 

Minidosé Monophasique

IP : 0.10

Lévonorgestrel  0.15   mg      EE 0.03 mg  x 21  cp   

TRIGYNON® 23.10 DH    TRINORDIOL® 28.60DH                  

Minidosé Triphasique

IP : 0,18

Lévonorgestrel  0.05   mg      EE 0.03 mg  x 06  cp   Lévonorgestrel   0.075   mg    EE 0.04 mg  x 05  cp

Lévonorgestrel   0.125   mg    EE 0.03 mg  x 10  cp

 

Progestatifs 3ème Génération :

            Désogestrel, Gestodène, et Norgestimate

MICRODIOL®        

28.40 DH 

Minidosé, Monophasique

 IP : 0,00 

cf Varnoline®

Désogestrel         0.15    mg   EE 0.03 mg  x 21 cp 

MERCILON®58.00 DH              

Minidosé Monophasique

IP : 0,05  

Désogestrel         0.15    mg   EE 0.02 mg  x 21 cp

GRACIAL®

61.20 DH

Minidosé Biphasique

IP :

Désogestrel         0.025    mg   EE 0.04 mg  x 07 cp Désogestrel         0.125    mg   EE 0.03 mg  x 15 cp

MONEVA®          64.80 DH   MINULET®          

69.70 DH                   

Minidosé Monophasique

IP : 0,06

Gestodène           0.075 mg    EE 0.03 mg  x 21  cp 

TRI-MINULET®83.60 D PHAEVA®

77.80 DH          

Minidosé Triphasique,

IP : 0,10

Gestodène           0.05    mg    EE 0.03 mg  x 06  cp 

Gestodène           0.07    mg    EE 0.04 mg  x 05  cp Gestodène      0.10    mg    EE 0.03 mg  x 10  cp  

 

 

Progestatifs de derniere Génération :

            Drospirédone (dérivé de la spironolacone)

JASMINE®        

100.00 DH   

JASMIN® en France

Minidosé, Monophasique

IP: 0,09

Drospirénone      3.00    mg   EE 0.03 mg  x 21 cp 

YAZ®

141.80 DH

 

IP: 0,41

Drospirénone      3.00    mg   EE 0.02 mg  x 24 cp 

 

Lire au sujet de la drospéridone notre article du 29 juin 2011 :  

 

Les pilules progestatives

 

Milligynon®

63.90 DH             

Progestative microdosée en continue

IP : 0,85

Progestatif de 1ère Génération    

Noréthistérone    0.600 mg       3 x 28 Cp

Microval®

13.95 DH        

Progestative microdosée en continue

IP : 1

environ

Progestatif de 2ème Génération

Lévonorgestrel   0.030 mg        1 x 28 Cp 

cerazette®

60.00 DH        

Progestative microdosée en continue

IP : 0.52

Progestatif de 3ème Génération

Désogestrel        0.075 mg        1 x 28 Cp 

 

 

CONTRACEPTION MACROPRGESTATIVE DISCONTINUE

 

- Il s’agit ici d’une contraception destinée essentiellement aux femmes en préménopose,

- les indications premières de ces produit restent : l’insuffisance lutéale, pathologies mammaire et endométriales bénignes, hémorragies fonctionnelles et ménorragies des fibromes.

- Dans cette liste seul le PRIMOLUT-NOR a eu l’AMM comme contraceptif, l’utilisation des autres produits se base sur leur effet antigonadotrope.

- Administration discontinue à la dose d’un cp par jour du 5ème au 25ème jour du cycle     

PRIMOLUT-NOR®

64.60 DH

Progestative macrodosé  en discontinue

 

Noréthistérone   10     mg       1 x 30 Cp

 1ère Génération    

AMM oui

LUTENYL®

75.40 DH

Progestative macrodosé 

 

Nomegstrol          5     mg       1  x 10 Cp

Dérivé de la 19-norprogestérone

SURGESTONE®

0,25 mg   71.90 DH   0,50 mg 113.30 DH                 

Progestative macrodosé 

 

 

Promegestone   0.25 mg          1 x 10 Cp   

Dérivé de la 19-norprogestérone

Promegestone   0.50 mg          1 x 10 Cp   

Dérivé de la 19-norprogestérone

Colprone®

62.50 DH

Progestative macrodosé

 

Medrogestone   5.00 mg          1 x 20 Cp

Dérivé de la 17-methylprogestérone

 

Les pilules du lendemain :

Utilisables, au maximum, dans les 3 jours qui suivent un rapport sexuel

NORLEVO®

94.00 DH

PROSTINOR®

90.00 DH

 

75 à 85 %

de succès

Lévonorgestrel  1.5 mg x 01 cp

[NB : 1 cp = 50 cp Microval®]

La 1ère prise le plus tôt possible, la 2ème 12 heurs après       

TETRAGYNON®

Lévonorgestrel   0.25   mg   

EE 0.05 mg                    x 04  cp

 

 

Sources :

- Actualités Pharmaceutiques N° 406 Mars 2002

- La revue prescrire mars 2004 n° 248 Tome 24 page 200

- El Mouatacim K et coll. : Les Cahiers du Méd. 2002 Jan T V (48) : 10-12.

- Revue médicale suisse :http://titan.medhyg.ch/mh/formation/print.php3?sid=31095

- Vidal

- Sites :AFFSSAPS, Pharmacorama

Contraceptives Essay

PAGE \* MERGEFORMAT 1 Contraceptives PAGE \* MERGEFORMAT 7


Final Research Paper

Donna B. Shelton

ELEMENTS OF UNIVERSITY COMPOSITION AND COMMUNICATION COM/172

April 1, 2013

Heidi Willis

Each person has control over when and if they become parents. It does not matter if you are married or single. Choosing a birth control method can be challenging, however, consult your doctor for favorable recommendations. There are many choices available, but there are also many factors that would have a heavy impact on your decision. A woman making the choice will naturally choose what they think is most convenient for them. Women choose implanted contraceptives for convenience, but are they more harmful than helpful? Even though implanted contraceptives are causing more problems than ever, they can protect you from unwanted pregnancies. According to the Federal Drug Administration, FDA or USFDA, (fda.gov) there is an estimated 150 million women worldwide that take some form of birth control. Research shows all contraceptives have many harmful side effects. Experience has shown that the most effective birth control can fail.

Most women use birth control to avoid unwanted pregnancies, to reduce the size of a cyst, and allow their bodies to menstruate normally. Most teenagers are introduced to birth control early to control acne, painful cramps, and hormone imbalances. With so many choices available, your doctor will make a recommendation based on your medical history. It seems like there is a different form available every year. When visiting your doctor yearly, you may have some thoughts about which method interests you. The most effective way to prevent pregnancy is abstinence.

It used to be that 'The Pill' and 'condoms' were the most common types of birth control. Currently, Yasmin, which is an oral contraceptive that was FDA-approved in 2001 for use in the United States; and the newer version of the drug Yaz, was approved for distribution in 2006 have been cited in approximately 1,100 lawsuits in the United States for causing substantial medical problems (FDA, 2001, 2013). Most women today do not make their contraceptive choices alone, they are being influenced by other women, advertisements, and appealing commercials to make their decisions. Some types include: Deprovera (the shot), Mirena, Nuva Ring, The Diaphragm, IUD, Norplant, Implanon, temperature method, and some even think of withdrawal as a method of birth control. Most of these alone are not going to protect you from sexually transmitted diseases. For as many options of birth control, there are just as many complications. As women, we face many demons to protect our bodies. Most women take all precautions to prevent accidents. When the time comes for you to make that choice of which birth control, just remember that no form protects from HIV/AIDS or other STDs. "The...

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